Trace Element Analysis

The isotopically labeled elements and compounds in the CIL library are amenable to a wide array of applications. Among them are research activities in conductivity, agriculture, botany, and biosample analysis (e.g., urine, bone). Increasingly performed is the testing of heavy metals (e.g., Hg, As, Cd) in cannabis-based products. As noted in the published literature (see example references below), the prevailing analytical technique for these types of applications is element-specific detection (e.g., ICP-MS).

Frequently Asked Questions

What are the three most commonly purchased elements/compounds and their quantity of supply? Isotopically enriched iron, sulfur, and lithium carbonate are the most commonly purchased elements/compounds. These are supplied in mg of element quantities.

Are there any shipping restrictions with the available products? Yes. For example, several products containing elemental boron and its compounds cannot be shipped to China and Hong Kong as they represent restricted products under the ECCN 1C011 and 1C225 regulations. Since other elements/compounds may be controlled in certain countries, please inquire for further details.

Can orders be customized based on element/compound and quantity of interest? Yes, please inquire.

What type of mineral oil is contained in the 6Li metal, and how would this be removed? White mineral oil. Prior to use, the oil can be removed by washing with solvent (e.g., petroleum ether).

Example References

Sogame, Y.; Tsukagoshi, A. 2020. Development of a liquid chromatography-inductively coupled plasma mass spectrometry method for the simultaneous determination of methylmercury and inorganic mercury in human blood. J Chromatogr B Analyt Technol Biomed Life Sci, 1136, 121855.  PMID: 31812836 
Galvez, L.; Rusz, M.; Schwaiger-Haber, M.; et al. 2019. Preclinical studies on metal based anticancer drugs as enabled by integrated metallomics and metabolomics. Metallomics, 11(10), 1716-1728. 
PMID: 31497817
Peixoto, R.R.A.; Fernández-Menéndez, S.; Fernández-Colomer, B.; et al. 2019. Quantitative speciation analysis for the in vivo study of iron metabolism and bioavailability from formula milk fortified with stable isotope-enriched iron oxo-hydroxide nanoparticles. J Anal Atom Spectrom, 34(4). 
Terán-Baamonde, J.; Soto-Ferreiro, R.M.; Carlosena-Zubieta, A.; et al. 2018. Isotope dilution inductively coupled plasma mass spectrometry to measure the bioaccessible fraction of chromium in sediments. Spectrochimica Acta B, 149, 15-21.
Terán-Baamonde, J.; Soto-Ferreiro, R.M.; Carlosena, A.; et al. 2018. Determination of cadmium in sediments by diluted HCl extraction and isotope dilution ICP-MS. Talanta, 186, 272-278. PMID: 29784360
Gaililea, S.B.O.; Moreno, S.F.  2017. Evaluation of sulfur isotopic enrichment of urine metabolites for the differentiation of healthy and prostate cancer mice after the administration of 34S labelled yeast. J Trace Elem Med Biol, 39, 155-161. PMID: 27908409
Hong-Hermesdorf, A.; Miethke, M.; Gallagher, S.D.; et. al 2014. Subcellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas. Nat Chem Biol, 10(12), 1034-1042. PMID: 25344811
Hsu, W.H.; Jiang, S.J.; Sahayam, A.C. 2013. Determination of Cu, As, Hg and Pb in vegetable oils by elctrothermal vaporization inductively coupled plasma mass spectrometry with palladium nanoparticles as modifier. Talanta, 117, 268-272. PMID: 24209340
Silva, K.I.; Saxena, S. 2013. Zn(II) ions substantially perturb Cu(II) ion coordination in amyloid-beta at physiological pH. J Phys Chem B, 117(32), 9386-9394. PMID: 23841511
Busto, ME.; Montes-Bayon, M.; Sanz-Medel, A. 2006. Accurate determination of human serum transferrin isoforms: Exploring metal-specific isotope dilution analysis as a quantitative proteomic tool. Anal Chem, 78(24), 8218-8226. PMID: 17165810
Chang, C.W.; Fennimore, A.M.; Afanasiev, A.; et al. 2006. Isotope effect on the thermal conductivity of boron nitride nanotubes. Phys Rev Lett, 97(8), 085901. PMID: 17026316
Encinar, J.R.; Villar, M.I.; Santamaria, V.G.; et al. 2001. Simultaneous determination of mono-, di-, and tributyltin in sediments by isotope dilution analysis using gas chromatography–ICPMS. Anal Chem, 73(13), 3174-3180. PMID: 11467570 
Matlock, M.M.; Howerton, B.S.; Atwood, D.A. 2001. Irreversible precipitation of mercury and lead. J Hazard Mater, 84(1), 73-82. PMID: 11376885