Modernization of Cosmetics Regulation Act of 2022 (MoCRA)

The average adult uses 12 pharmaceutical and personal care products (PPCPs) daily, ranging from skincare products, face and body cleansers, makeup, haircare products, and grooming products.Concern about environmental and human exposure to PPCPs has grown significantly, and in 2022 the United States Food and Drug Administration (FDA) passed The Modernization of Cosmetics Regulation Act of 2022 (MoCRA). MoCRA went into effect on December 29, 2023, and gives the FDA increased control over cosmetics, mandatory recall authority, improved labeling, and certain facility registration requirements.2 This update comes as the first significant change to the Federal Food, Drug, and Cosmetic Act since 1938.

While MoCRA provides increased oversight and involvement by the FDA in the cosmetics industry, it does not currently include initiatives to review or restrict chemicals that are harmful to human health. The FDA has recently submitted a request for $7.2 billion of the President’s fiscal year 2025 budget, of which $8 million would support the implementation and further development of MoCRA.3 Certain PPCPs have been described as endocrine disruptors, and recent human-exposure studies have focused on analysis of target compounds as well as their metabolites.

CIL offers an extensive line of high-quality stable isotope-labeled PPCP standards for use in the analysis of blood and serum in human exposure studies, as well as sewage sludge, drinking water, and wastewater in environmental studies.


Pharmaceutical and Personal Care Products Standards