酶标记

18O 原子掺入肽的 C 末端已成为比较定量蛋白质组学中使用的标记策略之一。这种酶标记技术的成功部分归因于相对较低的成本 18O 水,导致“重”肽分子量质量增加,以及共洗脱18O/16O 基于液相色谱 (LC) 的质谱 (MS) 实验中的肽对。

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用于质谱分析的稳定同位素标准品

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参考实例

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